Cyclohexadecanone

CAS number: 2550-52-9
IFRA Standard status: Concentration restricted

Last updated · 25-05-2026Record completeness90%

The information here describes the ingredient in general. Its possible sources may vary and do not necessarily show the origin or form used in a particular YUMA product. For product-specific information, check the relevant product page.

Description

Cyclohexadecanone is a fragrance ingredient featuring a distinct musk aroma with animalic undertones. Perfumers often describe the sensory profile as powdery and intense. Mainly used in personal care products such as perfumes, lotions, soaps, and shampoos, it imparts depth and longevity to a scent. Cyclohexadecanone is synthesized in laboratories by expert fragrance creators rather than derived from natural sources. Notably, modern production increasingly utilizes renewable raw materials, helping preserve natural global resources.

Additional information

Cyclohexadecanone belongs to the family of macrocyclic musks, a category of synthetic fragrance compounds that replaced natural animal-derived musks in modern perfumery, transforming how luxury fragrances are created.
Thanks to ingredients like cyclohexadecanone, the fragrance industry has significantly reduced the hunting of the musk deer and other animals traditionally used for perfume production, helping protect endangered species.
The powdery quality of cyclohexadecanone makes it a valuable component for crafting classic, elegant fragrance compositions reminiscent of traditional luxury French perfumes.

CAS number

2550-52-9

Other names

HomoexaltoneIsomuscone8-Cyclohexadecanone

Linked YUMA products

No YUMA products are linked to this ingredient

IFRA Standard status

The IFRA Standards form an industry self-regulatory system. They may prohibit or restrict the use of particular fragrance ingredients, or set specifications, according to end use. The status below reflects the IFRA data recorded for this ingredient. It is not a product certification and does not replace applicable law or assessment of the finished product.

Concentration restricted (R)

IFRA restrictions by category

IFRA categories group end uses by the type and level of exposure. A restriction or maximum concentration applies only to the stated category and does not automatically apply to another use. Check the related IFRA document for the applicable Standard version and its full conditions.

1. Lip products and children's toys
Max concentration0.25%
2. Deodorants and antiperspirants
Max concentration0.23%
3. Face cosmetics and masks
Max concentration4.4%

Regulatory information

The safety of cyclohexadecanone has been evaluated by the Research Institute for Fragrance Materials (RIFM), with a corresponding safety assessment published. Skin sensitization has been observed in a small percentage of individuals. This means that in a limited number of people, repeated contact may cause a temporary reaction such as redness, rash, or itching. To help prevent such reactions, the International Fragrance Association (IFRA) has established safe-use standards for cyclohexadecanone in home and personal care products. Although this potential exists, most people are unaffected. Every skin type is different, so consult a healthcare professional with any questions or if you notice reactions.

C All ingredients

Category	Max concentration
1. Lip products and children's toys	0.25%
2. Deodorants and antiperspirants	0.23%
3. Face cosmetics and masks	4.4%
4. Perfumes and fragranced products	4.3%
5A. Body lotions and powders	1.1%
5B. Face moisturizers and toners	1.1%
5C. Hand creams and sanitizers	1.1%
5D. Baby care products	0.37%
6. Oral care products	0.25%
7A. Rinse-off hair treatments	7.4%
7B. Leave-on hair products	7.4%
8. Intimate care products	0.37%
9. Rinse-off body products	8.4%
10A. Home care (non-aerosol)	0.98%
10B. Household aerosols and sprays	13%
11A. Products with minimal skin contact (no UV exposure)	0.37%
11B. Products with minimal skin contact (UV exposure)	0.37%
12. Products with no direct skin contact	–